Overall, I'm not worried. Things tend to balance themselves out, so if things get too out of hand, I figure Congress will step in to fix it. Plus, Dems are actually better for Big Business than Republicans are and I suspect we'll see quite a bit of this cash going to the Dem side. After all, it's not as if Big Money hadn't already infected Democratic coffers or policies. And if this drowns out enough little voices that even the Teabaggers feel impotent, we might find ourselves with the sort of campaign finance system we should have had all along.
And the main dynamic is that Big Business uses campaign cash to bribe Democrats to vote like Republicans, while Republicans extort it from Big Business by denying access to those who don't pay up. Sure, there are some conservative ideologue businessmen who willingly cough it up, but most of them don't give a damn who they give it to, just as long as they win. After all, there's no point in contributing to Republicans if they still can't get more than 30% approval ratings.
As things are, Dem politicos play nice because they still want that cash and lack the backbone to fight the system. But if they get beat up enough by corporate money, I have no doubt they'll finally find their spines. But I doubt it'll come to that. Corporate America already supports too many policies which are bad for Corporate America, and the more they let liberals fix our problems, the better it is for everyone.